Selected Important Safety Information
What is the most important information I should know about Saxenda®?
Serious side effects may happen in people who take Saxenda®, including:
Possible thyroid tumors, including cancer. Tell your health care professional if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rats and mice, Saxenda® and medicines that work like Saxenda® caused thyroid tumors, including thyroid cancer. It is not known if Saxenda® will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people.
Do not use Saxenda® if you or any of your family have ever had MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). See below for full Important Safety Information as well as Limitations of Use.
Saxenda® is an FDA-approved prescription injectable medicine that may help some adults with excess weight (body mass index [BMI] ≥27) who also have weight-related medical problems or obesity (BMI ≥30), lose weight and keep it off. Saxenda® should be used with a reduced-calorie meal plan and increased physical activity. Click here for full Indications and Usage.
Benefits of Saxenda®
You may have lost weight once or many times in the past. But keeping the weight off proved to be difficult. Learn how Saxenda® helped some adults lose weight and keep it off below. Then look up your co-pay and ask your health care professional if Saxenda® is right for you.
Results from a medical study showed significant weight loss
Along with a low-calorie meal plan and increased physical activity, some people in a medical study lost nearly 2.5 times more weight with Saxenda® versus placebo (17.3 lb vs 7 lb).a Study participants had an average starting weight of 234 lb and an average body mass index (BMI) of 38.
aThese results were from a 56-week trial of adults with excess weight (BMI ≥27) with at least 1 weight-related condition, or obesity (BMI ≥30), not including patients with type 2 diabetes. On average, 27% of people on Saxenda® and 34% on placebo did not complete the study. In the study, 62% of patients on Saxenda® lost ≥5% of their body weight (vs 34% placebo) and 34% lost ≥10% body weight (vs 15% placebo). Significant weight loss was only evaluated at 56 weeks, as per study design.
Get a personalized Weight Exploration Report
The Saxenda® Weight Exploration Report includes information on your past weight-loss efforts and current goals as well as important questions to ask your health care professional.
Changes in body weight over a year
The chart below is from a 1-year study of more than 3,500 adults.b It shows the average change in body weightc at 56 weeks. Individual results may vary.
bPatients without type 2 diabetes and with a BMI ≥30 or ≥27 with at least 1 weight-related condition, along with a reduced-calorie diet and physical activity.
cAverage starting weight was 233.9 lb and average starting BMI was 38.3.
dA reduction in body weight of 5% or more.
Use the Saxenda® pen at home or on the go
Saxenda® is a once-daily, self-injectable medicine that comes in a prefilled pen. Take your medicine each day at any time that is convenient for you, with or without food. Inject your dose under the skin (this is called subcutaneous injection) in your stomach area (abdomen), upper leg (thigh), or upper arm as instructed by your health care professional. Do not inject into a vein or muscle. Please see Saxenda® Instructions for Use for more information.
Store new, unused Saxenda® pens in the refrigerator between 36°F and 46°F (2°C to 8°C). After first use, store in a refrigerator or at room temperature between 59°F and 86°F (15°C to 30°C). Pens in use should be thrown away after 30 days even if they still have Saxenda® left in them. Don’t freeze Saxenda®. Saxenda® that has been frozen must not be used.
How Saxenda® works
Learn more about how Saxenda® works in the body to help you lose weight.
Are weight-related health conditions affecting you?
Reducing your waistline isn’t the only impact of weight loss. Taking off weight and keeping it off may help improve conditions such as high blood pressure and high cholesterol levels.
Saxenda® is not indicated for the treatment of high blood pressure or high cholesterol. It is not known if Saxenda® changes your risk of heart problems or stroke or of death due to heart problems or stroke.
While you are at rest, Saxenda® can increase your heart rate. Tell your health care professional if you feel your heart racing or pounding in your chest and it lasts for several minutes while taking Saxenda®.