Selected Important Safety Information
What is the most important information I should know about Saxenda®?
Serious side effects may happen in people who take Saxenda®, including:
Possible thyroid tumors, including cancer. Tell your health care professional if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rats and mice, Saxenda® and medicines that work like Saxenda® caused thyroid tumors, including thyroid cancer. It is not known if Saxenda® will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people.
Do not use Saxenda® if you or any of your family have ever had MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). See below for full Important Safety Information.
Saxenda® is an FDA-approved prescription injectable medicine that may help some adults with excess weight (body mass index [BMI] ≥27) who also have weight-related medical problems or obesity (BMI ≥30), lose weight and keep it off. Saxenda® should be used with a reduced-calorie meal plan and increased physical activity. Click here for full Indications and Usage.
Why Is It So Hard to Lose Weight?
One of the reasons why it's so hard to lose weight is because changes in your appetite hormone levels make it difficult to lose weight and keep it off. When you lose weight, your body’s natural response includes an increase in a key hunger hormone and a decrease in fullness hormones, undermining your ability to lose weight and keep it off.
Appetite hormones after weight loss
Your body works against you as you lose weight—making you feel hungrier and less full.
Losing weight IS possible
While it may be difficult to lose weight and keep it off, it can be done. It all starts with a plan. Here are some helpful tips:
Change your approach
- It’s not about finding a quick fix—it’s about focusing on your ongoing weight loss and weight management
- Increasing your physical activity and building a low-calorie meal plan that fits your lifestyle are key to reducing your weight
Take obesity seriously, just like other chronic diseases
- Losing weight and keeping it off requires a long-term plan
- If meal plan and physical activity changes alone are not enough, you may require medical intervention
Start with small steps
- Choose what you are willing to do
- Make it a part of your daily routine
- Take it 1 day at a time
- Work with your health care provider to create, monitor, and adjust your weight-management plan